CDK12 G923V: Gene Variant Detail - Cancer Knowledgebase (CKB)

Gene	CDK12
Variant	G923V
Impact List	missense
Protein Effect	unknown
Gene Variant Descriptions	CDK12 G923V lies within the protein kinase domain of the Cdk12 protein (PMID: 22512864). G923V has been identified in sequencing studies (PMID: 29906450, PMID: 32997692), but has not been biochemically characterized and therefore, its effect on Cdk12 protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths	CDK12 mutant CDK12 G923V

Variant Reference Transcript
All Transcripts

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Transcript	NM_016507.4
gDNA	chr17:g.39511630G>T
cDNA	c.2768G>T
Protein	p.G923V
Source Database	RefSeq
Genome Build	GRCh38/hg38

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Showing 1 to 86 of 86 entries

Transcript	gDNA	cDNA	Protein	Source Database	Genome Build
NM_015083	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
NM_015083.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
NM_015083.4	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
NM_016507	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
NM_016507.3	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
NM_016507.4	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_005257458	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_005257458.4	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524892	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524892.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524893	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524893.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524893.3	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524894	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524894.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524894.3	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524895	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524895.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524895.3	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524896	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524896.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524897	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524897.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524897.3	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524898	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524898.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524898.3	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524899	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524899.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524900	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524900.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524901	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524901.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524902	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524902.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524903	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524903.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524905	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524905.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524906	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524906.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524906.3	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524907	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524907.2	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_011524907.3	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024744	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024745	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024746	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024747	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024747.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024748	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024748.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024749	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024749.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024750	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024750.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024751	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024751.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024752	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_017024752.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_024450801.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436255.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436256.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436257.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436258.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436259.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436260.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436261.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436265.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436266.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436267.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436268.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436269.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436270.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436272.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436273.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436274.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436275.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436276.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436277.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436278.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436279.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436287.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436288.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436289.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38
XM_047436293.1	chr17:g.39511630G>T	c.2768G>T	p.G923V	RefSeq	GRCh38/hg38

Showing 1 to 86 of 86 entries

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CDK12 G923V - Gene Variant Detail

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