CDK12 L926I
Gene Variant Detail

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Gene CDK12
Variant L926I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions CDK12 L926I lies within the protein kinase domain of the Cdk12 protein (PMID: 22512864). L926I has not been characterized in the scientific literature and therefore, its effect on Cdk12 protein function is unknown (PubMed, May 2026).
Associated Drug Resistance
Category Variants Paths

CDK12 mutant CDK12 L926I

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Transcript NM_016507.4
gDNA chr17:g.39515738C>A
cDNA c.2776C>A
Protein p.L926I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_047436265.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436275.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
NM_015083.4 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524902 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_024450801.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524897.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524899 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_005257458.4 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524894.3 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524899.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436258.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524894 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524895 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024750 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524898.3 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436270.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436256.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524894.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524906.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524897 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524898 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524906 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436266.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436261.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024744 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524905.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436277.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524901 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524906.3 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024748 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436287.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024751.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524903 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436272.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436268.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024752 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_005257458 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524907.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
NM_016507.4 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524895.3 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524896 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524896.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024747 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524898.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524902.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024752.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436267.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024749.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436276.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524893 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436259.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436257.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524901.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024745 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524895.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
NM_016507.3 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524893.3 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436289.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024751 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
NM_015083 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
NM_016507 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024747.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436269.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024746 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524905 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524900.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524907.3 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436260.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436288.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024748.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524907 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024750.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524903.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524900 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436279.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_017024749 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
NM_015083.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524897.3 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436278.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436274.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436273.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_047436255.1 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38
XM_011524893.2 chr17:g.39515738C>A c.2776C>A p.L926I RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
CDK12 L926I unknown