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Gene CDKN2A
Variant D108V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions CDKN2A D108V does not lie within any known functional domains of the Cdkn2a protein (UniProt.org). D108V has been identified in sequencing studies (PMID: 29301828, PMID: 26919633, PMID: 35620707), but has not been biochemically characterized and therefore, its effect on Cdkn2a protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

CDKN2A mutant CDKN2A D108V

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Transcript NM_000077.5
gDNA chr9:g.21971036T>A
cDNA c.323A>T
Protein p.D108V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000077 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38
NM_000077.4 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38
NM_000077.5 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38
XM_011517675.3 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38
NM_001195132.2 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38
XM_011517675.2 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38
XM_011517676.3 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38
NM_001195132 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38
XM_011517676 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38
XM_011517676.2 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38
XM_011517675 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38
NM_001195132.1 chr9:g.21971036T>A c.323A>T p.D108V RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Protein Effect Treatment Approaches
CDKN2A D108V unknown