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CDKN2A W110* - Gene Variant Detail

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Gene CDKN2A
Variant W110*
Impact List nonsense
Protein Effect loss of function
Gene Variant Descriptions CDKN2A W110* results in a premature truncation of the Cdkn2a protein at amino acid 110 of 156 (UniProt.org). W110* confers a loss of function to the Cdkn2a protein as demonstrated by loss of Cdk binding and failure to restrict cell-cycle progression in culture (PMID: 9053859, PMID: 8668202).
Associated Drug Resistance
Category Variants Paths

CDKN2A mutant CDKN2A inact mut CDKN2A W110*

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Transcript NM_000077.5
gDNA chr9:g.21971030C>T
cDNA c.329G>A
Protein p.W110*
Source Database RefSeq
Genome Build GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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