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Gene RAD51C
Variant E45D
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RAD51C E45D lies within a region of the Rad51c protein required for Holliday junction resolution activity (UniProt.org). E45D has been identified in sequencing studies (PMID: 24185509), but has not been biochemically characterized and therefore, its effect on Rad51c protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

RAD51C mutant RAD51C E45D

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Transcript NM_058216.3
gDNA chr17:g.58692778G>C
cDNA c.135G>C
Protein p.E45D
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002876.3 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
XM_006722001.5 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
XM_006722001.4 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
NM_058216 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
XM_006722001 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
XM_047436505.1 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
NM_058216.3 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
NM_058216.2 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
XM_006722002 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
NM_002876.4 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
NM_002876 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
XM_006722002.4 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38
XM_006722002.5 chr17:g.58692778G>C c.135G>C p.E45D RefSeq GRCh38/hg38

Filtering

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries