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Gene RAD51C
Variant K320M
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RAD51C K320M does not lie within any known functional domains of the Rad51c protein (UniProt.org). K320M has been identified in sequencing studies (PMID: 22980975), but has not been biochemically characterized and therefore, its effect on Rad51c protein function is unknown (PubMed, May 2024).
Associated Drug Resistance
Category Variants Paths

RAD51C mutant RAD51C K320M

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Transcript NM_058216.3
gDNA chr17:g.58724094A>T
cDNA c.959A>T
Protein p.K320M
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_058216.2 chr17:g.58724094A>T c.959A>T p.K320M RefSeq GRCh38/hg38
XM_006722002.4 chr17:g.58732538_58732539delAAinsTG c.959_960delAAinsTG p.K320M RefSeq GRCh38/hg38
NM_058216 chr17:g.58724094A>T c.959A>T p.K320M RefSeq GRCh38/hg38
XM_006722002 chr17:g.58732538_58732539delAAinsTG c.959_960delAAinsTG p.K320M RefSeq GRCh38/hg38
XM_006722001 chr17:g.58724094A>T c.959A>T p.K320M RefSeq GRCh38/hg38
NM_058216.3 chr17:g.58724094A>T c.959A>T p.K320M RefSeq GRCh38/hg38
XM_006722001.5 chr17:g.58724094A>T c.959A>T p.K320M RefSeq GRCh38/hg38
XM_006722001.4 chr17:g.58724094A>T c.959A>T p.K320M RefSeq GRCh38/hg38
XM_006722002.5 chr17:g.58732538_58732539delAAinsTG c.959_960delAAinsTG p.K320M RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References