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RAD51D S298Y - Gene Variant Detail

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Gene RAD51D
Variant S298Y
Impact List missense
Protein Effect unknown
Gene Variant Descriptions RAD51D S298Y does not lie within any known functional domains of the Rad51d protein (UniProt.org). S298Y has not been characterized in the scientific literature and therefore, its effect on Rad51d protein function is unknown (PubMed, Dec 2024).
Associated Drug Resistance
Category Variants Paths

RAD51D mutant RAD51D S298Y

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Transcript NM_002878.4
gDNA chr17:g.35101211G>T
cDNA c.893C>A
Protein p.S298Y
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002878.3 chr17:g.35101211G>T c.893C>A p.S298Y RefSeq GRCh38/hg38
NM_002878 chr17:g.35101211G>T c.893C>A p.S298Y RefSeq GRCh38/hg38
NM_002878.4 chr17:g.35101211G>T c.893C>A p.S298Y RefSeq GRCh38/hg38

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
RAD51D mutant breast cancer not applicable N/A Guideline Risk Factor Germline RAD51D mutations are associated with increased risk of developing breast cancer (NCCN.org). detail...
RAD51D mutant ovarian cancer not applicable N/A Guideline Risk Factor Germline RAD51D mutations are associated with increased risk of developing ovarian cancer (NCCN.org). detail...