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| Gene | FBXW7 |
| Variant | del |
| Impact List | deletion |
| Protein Effect | loss of function |
| Gene Variant Descriptions | FBXW7 del indicates a deletion of the FBXW7 gene. |
| Associated Drug Resistance | |
| Category Variants Paths |
FBXW7 mutant FBXW7 inact mut FBXW7 del |
| Clinical Trial | Phase | Therapies | Title | Recruitment Status | Covered Countries | Other Countries |
|---|---|---|---|---|---|---|
| NCT05867251 | Phase Ib/II | ARTS-021 + Fulvestrant + Ribociclib ARTS-021 + Letrozole + Ribociclib ARTS-021 + Fulvestrant + Palbociclib ARTS-021 + Letrozole + Palbociclib ARTS-021 + Carboplatin Abemaciclib + ARTS-021 + Fulvestrant Abemaciclib + ARTS-021 + Letrozole ARTS-021 + Fulvestrant ARTS-021 | Study of AVZO-021 in Patients With Advanced Solid Tumors | Recruiting | USA | AUS | 0 |