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Gene ATR
Variant E2378V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ATR E2378V lies within the PI3K/PI4K domain of the Atr protein (UniProt.org). E2378V has not been characterized in the scientific literature and therefore, its effect on Atr protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

ATR mutant ATR E2378V

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Transcript NM_001184.4
gDNA chr3:g.142461999T>A
cDNA c.7133A>T
Protein p.E2378V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001184.4 chr3:g.142461999T>A c.7133A>T p.E2378V RefSeq GRCh38/hg38
NM_001184 chr3:g.142461999T>A c.7133A>T p.E2378V RefSeq GRCh38/hg38
NM_001184.3 chr3:g.142461999T>A c.7133A>T p.E2378V RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References