ROS1 T145P
Gene Variant Detail

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Gene ROS1
Variant T145P
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ROS1 T145P lies within fibronectin type-III domain 1 of the Ros1 protein (UniProt.org). T145P has been identified in the scientific literature (PMID: 29981866, PMID: 36422072, PMID: 38927739), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Sep 2025).
Associated Drug Resistance
Category Variants Paths

ROS1 mutant ROS1 T145P

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Transcript NM_002944.3
gDNA chr6:g.117404285T>G
cDNA c.433A>C
Protein p.T145P
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_002944.2 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38
XM_017011173.1 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38
NM_002944.3 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38
XM_017011173 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38
XM_017011172 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38
XM_017011172.1 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38
NM_002944 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38
XM_017011172.2 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38
XM_011536051 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38
XM_011536051.2 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38
XM_017011173.2 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38
XM_011536051.3 chr6:g.117404285T>G c.433A>C p.T145P RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries