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Gene ATR
Variant L1361V
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ATR L1361V lies within HEAT repeat 2 of the Atr protein (UniProt.org). L1361V has been identified in sequencing studies (PMID: 22895193), but has not been biochemically characterized and therefore, its effect on Atr protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

ATR mutant ATR L1361V

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Transcript NM_001184.4
gDNA chr3:g.142524064A>C
cDNA c.4081T>G
Protein p.L1361V
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011512924 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38
NM_001184.4 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38
XM_011512924.1 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38
NM_001354579.1 chr3:g.142519778G>C c.4081C>G p.L1361V RefSeq GRCh38/hg38
XM_047448360.1 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38
XM_047448361.1 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38
XM_011512926 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38
XM_017006643 chr3:g.142519778G>C c.4081C>G p.L1361V RefSeq GRCh38/hg38
XM_047448364.1 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38
NM_001184 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38
NM_001354579.2 chr3:g.142519778G>C c.4081C>G p.L1361V RefSeq GRCh38/hg38
XM_047448362.1 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38
XM_047448363.1 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38
XM_011512924.2 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38
NM_001184.3 chr3:g.142524064A>C c.4081T>G p.L1361V RefSeq GRCh38/hg38

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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References