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Gene ATR
Variant L1746I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ATR L1746I lies within the FAT domain of the Atr protein (UniProt.org). L1746I has not been characterized in the scientific literature and therefore, its effect on Atr protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

ATR mutant ATR L1746I

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Transcript NM_001184.4
gDNA chr3:g.142503414G>T
cDNA c.5236C>A
Protein p.L1746I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
XM_011512925.1 chr3:g.142498733A>T c.5236T>A p.L1746I RefSeq GRCh38/hg38
XM_011512924.1 chr3:g.142503420A>T c.5236T>A p.L1746I RefSeq GRCh38/hg38
XM_011512924 chr3:g.142503420A>T c.5236T>A p.L1746I RefSeq GRCh38/hg38
XM_047448361.1 chr3:g.142503420A>T c.5236T>A p.L1746I RefSeq GRCh38/hg38
NM_001184.4 chr3:g.142503414G>T c.5236C>A p.L1746I RefSeq GRCh38/hg38
XM_047448360.1 chr3:g.142503420A>T c.5236T>A p.L1746I RefSeq GRCh38/hg38
NM_001184 chr3:g.142503414G>T c.5236C>A p.L1746I RefSeq GRCh38/hg38
XM_011512926 chr3:g.142503420A>T c.5236T>A p.L1746I RefSeq GRCh38/hg38
XM_011512924.2 chr3:g.142503420A>T c.5236T>A p.L1746I RefSeq GRCh38/hg38
XM_047448363.1 chr3:g.142503414G>T c.5236C>A p.L1746I RefSeq GRCh38/hg38
XM_047448364.1 chr3:g.142503420A>T c.5236T>A p.L1746I RefSeq GRCh38/hg38
NM_001184.3 chr3:g.142503414G>T c.5236C>A p.L1746I RefSeq GRCh38/hg38
XM_047448362.1 chr3:g.142503420A>T c.5236T>A p.L1746I RefSeq GRCh38/hg38
XM_011512925.2 chr3:g.142498733A>T c.5236T>A p.L1746I RefSeq GRCh38/hg38
XM_011512925 chr3:g.142498733A>T c.5236T>A p.L1746I RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

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  • Click on any column header arrows to sort by that column
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References