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Gene ATR
Variant L2593I
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ATR L2593I does not lie within any known functional domains of the Atr protein (UniProt.org). L2593I has been identified in sequencing studies (PMID: 29316426), but has not been biochemically characterized and therefore, its effect on Atr protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

ATR mutant ATR L2593I

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Transcript NM_001184.4
gDNA chr3:g.142449587G>T
cDNA c.7777C>A
Protein p.L2593I
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001184.3 chr3:g.142449587G>T c.7777C>A p.L2593I RefSeq GRCh38/hg38
NM_001184 chr3:g.142449587G>T c.7777C>A p.L2593I RefSeq GRCh38/hg38
NM_001184.4 chr3:g.142449587G>T c.7777C>A p.L2593I RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
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Clinical Trial Phase Therapies Title Recruitment Status Covered Countries Other Countries