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Gene TP53
Variant M237_S241del
Impact List deletion
Protein Effect unknown
Gene Variant Descriptions TP53 M237_S241del results in the deletion of five amino acids in the DNA-binding domain of the Tp53 protein (PMID: 22713868). M237_S241del has not been characterized in the scientific literature and therefore, its effect on Tp53 protein function is unknown (PubMed, Feb 2024).
Associated Drug Resistance
Category Variants Paths

TP53 mutant TP53 exon7 TP53 M237_S241del

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Transcript NM_000546.6
gDNA chr17:g.7674241_7674255del15
cDNA c.709_723del15
Protein p.M237_S241del
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_000546.6 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_000546.5 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001126113.2 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001126112.2 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001407270.1 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001407266.1 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001407268.1 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001407262.1 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001126112 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001407264.1 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001126113.3 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001126114.3 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_000546 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001126112.3 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001126114.2 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001126113 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38
NM_001126114 chr17:g.7674241_7674255del15 c.709_723del15 p.M237_S241del RefSeq GRCh38/hg38

Filtering

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
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  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References