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Gene ATR
Variant S684Y
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ATR S684Y does not lie within any known functional domains of the Atr protein (UniProt.org). S684Y has not been characterized in the scientific literature and therefore, its effect on Atr protein function is unknown (PubMed, Aug 2024).
Associated Drug Resistance
Category Variants Paths

ATR mutant ATR S684Y

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Transcript NM_001184.4
gDNA chr3:g.142556410G>T
cDNA c.2051C>A
Protein p.S684Y
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001184.3 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38
XM_011512924.1 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38
XM_011512924 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38
XM_047448363.1 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38
XM_047448364.1 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38
XM_011512924.2 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38
XM_047448360.1 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38
NM_001184 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38
NM_001184.4 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38
XM_047448362.1 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38
XM_047448361.1 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38
XM_011512926 chr3:g.142556410G>T c.2051C>A p.S684Y RefSeq GRCh38/hg38

Filtering

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References