ATR Y2637C
Gene Variant Detail

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Gene ATR
Variant Y2637C
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ATR Y2637C lies within the FATC domain of the Atr protein (UniProt.org). Y2637C has been identified in sequencing studies (PMID: 29884412, PMID: 25275298, PMID: 25151357), but has not been biochemically characterized and therefore, its effect on Atr protein function is unknown (PubMed, Dec 2025).
Associated Drug Resistance
Category Variants Paths

ATR mutant ATR Y2637C

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Transcript NM_001184.4
gDNA chr3:g.142449454T>C
cDNA c.7910A>G
Protein p.Y2637C
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_001184.3 chr3:g.142449454T>C c.7910A>G p.Y2637C RefSeq GRCh38/hg38
NM_001184.4 chr3:g.142449454T>C c.7910A>G p.Y2637C RefSeq GRCh38/hg38
NM_001184 chr3:g.142449454T>C c.7910A>G p.Y2637C RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
  • Click on any column header arrows to sort by that column
  • Hold down the Shift key and click multiple columns to sort by more than one column. Be sure to set ascending or descending order for a given column before moving on to the next column.

Molecular Profile Protein Effect Treatment Approaches
ATR Y2637C unknown