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Gene ARID1A
Variant R1223C
Impact List missense
Protein Effect unknown
Gene Variant Descriptions ARID1A R1223C does not lie within any known functional domains of the Arid1a protein (UniProt.org). R1223C has been identified in sequencing studies (PMID: 22810696, PMID: 28292439, PMID: 30675285), but has not been biochemically characterized and therefore, its effect on Arid1a protein function is unknown (PubMed, Oct 2024).
Associated Drug Resistance
Category Variants Paths

ARID1A mutant ARID1A R1223C

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Transcript NM_006015.6
gDNA chr1:g.26772939C>T
cDNA c.3667C>T
Protein p.R1223C
Source Database RefSeq
Genome Build GRCh38/hg38
Transcript gDNA cDNA Protein Source Database Genome Build
NM_006015.5 chr1:g.26772939C>T c.3667C>T p.R1223C RefSeq GRCh38/hg38
NM_139135.3 chr1:g.26772939C>T c.3667C>T p.R1223C RefSeq GRCh38/hg38
NM_139135.4 chr1:g.26772939C>T c.3667C>T p.R1223C RefSeq GRCh38/hg38
NM_006015 chr1:g.26772939C>T c.3667C>T p.R1223C RefSeq GRCh38/hg38
NM_139135 chr1:g.26772939C>T c.3667C>T p.R1223C RefSeq GRCh38/hg38
NM_006015.6 chr1:g.26772939C>T c.3667C>T p.R1223C RefSeq GRCh38/hg38

Filtering

  • Case insensitive filtering will display rows if any text in any cell matches the filter term
  • Use simple literal full or partial string matches
  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

Sorting

  • Generally, the default sort order for tables is set to be first column ascending; however, specific tables may set a different default sort order.
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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References