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| Gene | ARID1A |
| Variant | R1658Q |
| Impact List | missense |
| Protein Effect | unknown |
| Gene Variant Descriptions | ARID1A R1658Q lies within the GR binding domain of the Arid1a protein (PMID: 23208470). R1658Q has not been characterized in the scientific literature and therefore, its effect on Arid1a protein function is unknown (PubMed, Feb 2026). |
| Associated Drug Resistance | |
| Category Variants Paths |
ARID1A mutant ARID1A R1658Q |
| Transcript | NM_006015.6 |
| gDNA | chr1:g.26775200G>A |
| cDNA | c.4973G>A |
| Protein | p.R1658Q |
| Source Database | RefSeq |
| Genome Build | GRCh38/hg38 |
| Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
|---|---|---|---|---|---|
| NM_006015 | chr1:g.26775200G>A | c.4973G>A | p.R1658Q | RefSeq | GRCh38/hg38 |
| NM_006015.5 | chr1:g.26775200G>A | c.4973G>A | p.R1658Q | RefSeq | GRCh38/hg38 |
| NM_006015.6 | chr1:g.26775200G>A | c.4973G>A | p.R1658Q | RefSeq | GRCh38/hg38 |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|