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Gene | ROS1 |
Variant | K2003I |
Impact List | missense |
Protein Effect | unknown |
Gene Variant Descriptions | ROS1 K2003I lies within the protein kinase domain of the Ros1 protein (UniProt.org). K2003I has been identified in the scientific literature (PMID: 33489820, PMID: 25351743), but has not been biochemically characterized and therefore, its effect on Ros1 protein function is unknown (PubMed, Mar 2024). |
Associated Drug Resistance | |
Category Variants Paths |
ROS1 mutant ROS1 K2003I |
Transcript | NM_002944.3 |
gDNA | chr6:g.117317270T>A |
cDNA | c.6008A>T |
Protein | p.K2003I |
Source Database | RefSeq |
Genome Build | GRCh38/hg38 |
Transcript | gDNA | cDNA | Protein | Source Database | Genome Build |
---|---|---|---|---|---|
NM_002944 | chr6:g.117317270T>A | c.6008A>T | p.K2003I | RefSeq | GRCh38/hg38 |
NM_002944.3 | chr6:g.117317270T>A | c.6008A>T | p.K2003I | RefSeq | GRCh38/hg38 |
NM_002944.2 | chr6:g.117317270T>A | c.6008A>T | p.K2003I | RefSeq | GRCh38/hg38 |
Molecular Profile | Protein Effect | Treatment Approaches |
---|---|---|
ROS1 K2003I | unknown |