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FGFR2 T730S - Gene Variant Detail

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Gene FGFR2
Variant T730S
Impact List missense
Protein Effect no effect
Gene Variant Descriptions FGFR2 T730S (corresponds to T729S in the canonical isoform) lies within the protein kinase domain of the Fgfr2 protein (UniProt.org). T730S has activity similar to wild-type Fgfr2 as demonstrated by equivalent substrate phosphorylation and the lack of oncogenic cell transformation (PMID: 26048680).
Associated Drug Resistance
Category Variants Paths

FGFR2 mutant FGFR2 T730S

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Transcript NM_022970.4
gDNA chr10:g.121485404G>C
cDNA c.2189C>G
Protein p.T730S
Source Database RefSeq
Genome Build GRCh38/hg38

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  • Separate multiple filter terms with a space. Any order may be used (i. e. a b c and c b a are equivalent )
  • Filtering will only apply to rows that are already loaded on the page. Filtering has no impact on query parameters.
  • Use quotes to match on a longer phrase with spaces (i.e. "mtor c1483f")

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