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Molecular Profile | BRAF G469L |
Therapy | Vemurafenib |
Indication/Tumor Type | lung adenocarcinoma |
Response Type | no benefit |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF G469L | lung adenocarcinoma | no benefit | Vemurafenib | Case Reports/Case Series | Actionable | In a clinical case study, a lung adenocarcinoma patient harboring BRAF G469L did not respond to Zelboraf (vemurafenib) therapy (PMID: 24035431). | 24035431 |
PubMed Id | Reference Title | Details |
---|---|---|
(24035431) | Lung adenocarcinoma with BRAF G469L mutation refractory to vemurafenib. | Full reference... |