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Molecular Profile | TP53 loss |
Therapy | Ad5CMV-p53 gene |
Indication/Tumor Type | colorectal cancer |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
TP53 loss | colorectal cancer | predicted - sensitive | Ad5CMV-p53 gene | Preclinical | Actionable | In a preclinical study, Ad5CMV-p53 gene therapy suppressed growth of allograft colorectal cancer in rat models (PMID: 15608394). | 15608394 |
PubMed Id | Reference Title | Details |
---|---|---|
(15608394) | In vivo recombinant adenovirus-mediated p53 gene therapy in a syngeneic rat model for colorectal cancer. | Full reference... |