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Molecular Profile | TP53 wild-type |
Therapy | NSC319726 |
Indication/Tumor Type | lung large cell carcinoma |
Response Type | resistant |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
TP53 wild-type | lung large cell carcinoma | resistant | NSC319726 | Preclinical - Cell line xenograft | Actionable | In a preclinical study, NSC319726 did not inhibit tumor growth in xenograft models of TP53 wild-type lung large cell carcinoma (PMID: 22624712). | 22624712 |
PubMed Id | Reference Title | Details |
---|---|---|
(22624712) | Allele-specific p53 mutant reactivation. | Full reference... |