Missing content? – Request curation!
Request curation for specific Genes, Variants, or PubMed publications.
Have questions, comments, or suggestions? - Let us know!
Email us at : ckbsupport@genomenon.com
Molecular Profile | NRAS G13D |
Therapy | 3144 |
Indication/Tumor Type | adult T-cell leukemia/lymphoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
NRAS G13D | adult T-cell leukemia/lymphoma | sensitive | 3144 | Preclinical - Cell culture | Actionable | In a preclinical study, 3144 inhibited growth of patient-derived T-cell acute lymphocytic leukemia cells harboring NRAS G13D in culture (PMID: 28235199). | 28235199 |
PubMed Id | Reference Title | Details |
---|---|---|
(28235199) | Multivalent Small-Molecule Pan-RAS Inhibitors. | Full reference... |