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| Molecular Profile | AXL positive |
| Therapy | 20G7-D9 |
| Indication/Tumor Type | triple-receptor negative breast cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| AXL positive | triple-receptor negative breast cancer | sensitive | 20G7-D9 | Preclinical - Pdx | Actionable | In a preclinical study, 20G7-D9 inhibited tumor growth in triple-negative breast cancer cell line xenograft models with high or moderate AXL expression and in AXL-expressing patient-derived xenograft (PDX) models (PMID: 27923843). | 27923843 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (27923843) | Therapeutic Activity of Anti-AXL Antibody against Triple-Negative Breast Cancer Patient-Derived Xenografts and Metastasis. | Full reference... |