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Molecular Profile | TP53 positive |
Therapy | MVAp53 |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
TP53 positive | Advanced Solid Tumor | sensitive | MVAp53 | Phase I | Actionable | In a phase I study, Ankara (MVAp53) demonstrated safety and efficacy in patients with metastatic colon, gastric and pancreas cancer stained positive for p53 (J Clin Oncol 31, 2013 (suppl; abstr 3089)). | detail... |
PubMed Id | Reference Title | Details |
---|---|---|
A phase I study of an MVA vaccine targeting p53 in cancer. | Full reference... |