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Molecular Profile | BRAF mut PTEN mut |
Therapy | ST-162 |
Indication/Tumor Type | melanoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF mut PTEN mut | melanoma | predicted - sensitive | ST-162 | Preclinical - Cell line xenograft | Actionable | In a preclinical study, ST-162 resulted in tumor regression in a melanoma cell line xenograft model co-harboring mutations in BRAF and PTEN (PMID: 28775144). | 28775144 |
PubMed Id | Reference Title | Details |
---|---|---|
(28775144) | A Bifunctional MAPK/PI3K Antagonist for Inhibition of Tumor Growth and Metastasis. | Full reference... |