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| Molecular Profile | SRC positive |
| Therapy | Bosutinib |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| SRC positive | Advanced Solid Tumor | predicted - sensitive | Bosutinib | Preclinical - Cell culture | Actionable | In a preclinical study, Bosulif (bosutinib) inhibited invasion and migration of Src-positive cells in culture (PMID: 18483306). | 18483306 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (18483306) | SKI-606 (bosutinib), a novel Src kinase inhibitor, suppresses migration and invasion of human breast cancer cells. | Full reference... |