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| Molecular Profile | FGFR2 amp |
| Therapy | Derazantinib |
| Indication/Tumor Type | stomach cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR2 amp | stomach cancer | sensitive | Derazantinib | Preclinical - Cell culture | Actionable | In a preclinical study, Derazantinib (ARQ 087) inhibited Fgfr signaling and growth of gastric cancer cells harboring FGFR2 amplification in culture (PMID: 27627808). | 27627808 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (27627808) | Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation. | Full reference... |