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Molecular Profile | KIT over exp |
Therapy | Imatinib |
Indication/Tumor Type | seminoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
KIT over exp | seminoma | sensitive | Imatinib | Case Reports/Case Series | Actionable | In a clinical case study, Gleevec (imatinib) in conjunction with third-line chemotherapy resulted in a complete response in a patient with stage IV chemoresistant pure seminoma with KIT overexpression (PMID: 18751412). | 18751412 |
PubMed Id | Reference Title | Details |
---|---|---|
(18751412) | Complete response after imatinib mesylate administration in a patient with chemoresistant stage IV seminoma. | Full reference... |