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| Molecular Profile | KIT over exp |
| Therapy | Imatinib |
| Indication/Tumor Type | seminoma |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| KIT over exp | seminoma | sensitive | Imatinib | Case Reports/Case Series | Actionable | In a clinical case study, Gleevec (imatinib) in conjunction with third-line chemotherapy resulted in a complete response in a patient with stage IV chemoresistant pure seminoma with KIT overexpression (PMID: 18751412). | 18751412 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (18751412) | Complete response after imatinib mesylate administration in a patient with chemoresistant stage IV seminoma. | Full reference... |