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| Molecular Profile | APC mutant |
| Therapy | TetMYB |
| Indication/Tumor Type | colon adenoma |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| APC mutant | colon adenoma | predicted - sensitive | TetMYB | Preclinical | Actionable | In a preclinical study, TetMYB treatment resulted in improved median survival compared to control (356 vs 183 days) in APC-driven mouse models of colon adenoma (Gastroenterology, Volume 154, Issue 6, Supplement 1, May 2018, Pages S-1269). | detail... |
| PubMed Id | Reference Title | Details |
|---|---|---|
| Cancer Vaccine Targeting MYB in Colorectal Cancer: From Pre-Clinical Model to Clinical Trial | Full reference... |