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Molecular Profile | APC mutant |
Therapy | TetMYB |
Indication/Tumor Type | colon adenoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
APC mutant | colon adenoma | predicted - sensitive | TetMYB | Preclinical | Actionable | In a preclinical study, TetMYB treatment resulted in improved median survival compared to control (356 vs 183 days) in APC-driven mouse models of colon adenoma (Gastroenterology, Volume 154, Issue 6, Supplement 1, May 2018, Pages S-1269). | detail... |
PubMed Id | Reference Title | Details |
---|---|---|
Cancer Vaccine Targeting MYB in Colorectal Cancer: From Pre-Clinical Model to Clinical Trial | Full reference... |