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| Molecular Profile | BRAF mutant |
| Therapy | Belvarafenib |
| Indication/Tumor Type | thyroid cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| BRAF mutant | thyroid cancer | sensitive | Belvarafenib | Preclinical - Cell culture | Actionable | In a preclinical study, Belvarafenib (HM95573) inhibited growth of BRAF mutant thyroid cancer cells in culture (Cancer Res 2015;75(15 Suppl):Abstract nr 2607). | detail... |
| PubMed Id | Reference Title | Details |
|---|---|---|
| Antitumor activity of the selective RAF inhibitor HM95573 in solid tumors and hematologic malignancies | Full reference... |