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Molecular Profile | NRAS mutant |
Therapy | Belvarafenib |
Indication/Tumor Type | leukemia |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
NRAS mutant | leukemia | sensitive | Belvarafenib | Preclinical - Cell culture | Actionable | In a preclinical study, Belvarafenib (HM95573) inhibited growth of NRAS mutant leukemia cells in culture (Cancer Res 2015;75(15 Suppl):Abstract nr 2607). | detail... |
PubMed Id | Reference Title | Details |
---|---|---|
Antitumor activity of the selective RAF inhibitor HM95573 in solid tumors and hematologic malignancies | Full reference... |