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Molecular Profile NRAS mutant
Therapy Belvarafenib
Indication/Tumor Type leukemia
Response Type sensitive

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Molecular Profile Indication/Tumor Type Response Type Therapy Name Approval Status Evidence Type Efficacy Evidence References
NRAS mutant leukemia sensitive Belvarafenib Preclinical - Cell culture Actionable In a preclinical study, Belvarafenib (HM95573) inhibited growth of NRAS mutant leukemia cells in culture (Cancer Res 2015;75(15 Suppl):Abstract nr 2607). detail...
PubMed Id Reference Title Details
Antitumor activity of the selective RAF inhibitor HM95573 in solid tumors and hematologic malignancies Full reference...