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Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
KIT T632I | melanoma | predicted - resistant | Imatinib | Case Reports/Case Series | Actionable | In a clinical case study, Gleevec (imatinib) treatment resulted in worsened condition and continued disease progression and metastasis in a patient with metastatic melanoma harboring KIT T632I (PMID: 31043947). | 31043947 |
PubMed Id | Reference Title | Details |
---|---|---|
(31043947) | Lack of Response to Imatinib in Melanoma Carrying Rare KIT Mutation p.T632I. | Full reference... |