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| Molecular Profile | KDR act mut |
| Therapy | Sunitinib |
| Indication/Tumor Type | bladder urothelial carcinoma |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| KDR act mut | bladder urothelial carcinoma | predicted - sensitive | Sunitinib | Phase II | Actionable | In a Phase II clinical trial of patients with metastatic urothelial cancer, Sutent (sunitinib) demonstrated limited antitumor activity, warranting further investigation of VEGF pathways as a therapeutic target (PMID: 20142593). | 20142593 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (20142593) | Phase II study of sunitinib in patients with metastatic urothelial cancer. | Full reference... |