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| Molecular Profile | FGFR1 amp |
| Therapy | Dovitinib |
| Indication/Tumor Type | Her2-receptor positive breast cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR1 amp | Her2-receptor positive breast cancer | sensitive | Dovitinib | Phase II | Actionable | In a Phase II trial, Dovitinib (TKI258) promoted 6-month stable disease in Erbb2 (Her2)-positive breast cancer patients with FGFR1 amplification (PMID: 23658459). | 23658459 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (23658459) | Targeting FGFR with dovitinib (TKI258): preclinical and clinical data in breast cancer. | Full reference... |