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Molecular Profile | BRAF V600E PTEN loss |
Therapy | unspecified PD-1 antibody + VE800 |
Indication/Tumor Type | melanoma |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF V600E PTEN loss | melanoma | sensitive | unspecified PD-1 antibody + VE800 | Preclinical | Actionable | In a preclinical study, PD-1 antibody treatment supplemented with VE800 inhibited tumor growth in a transgenic mouse model of melanoma harboring PTEN loss and BRAF V600E (PMID: 30675064). | 30675064 |
PubMed Id | Reference Title | Details |
---|---|---|
(30675064) | A defined commensal consortium elicits CD8 T cells and anti-cancer immunity. | Full reference... |