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| Molecular Profile | CSF1R Y561_I564del |
| Therapy | BLZ945 |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| CSF1R Y561_I564del | Advanced Solid Tumor | sensitive | BLZ945 | Preclinical - Cell culture | Actionable | In a preclinical study, transformed cells expressing CSF1R Y561_I564del demonstrated sensitivity to treatment with BLZ945 in culture (PMID: 31768065). | 31768065 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (31768065) | Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms. | Full reference... |