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| Molecular Profile | APC inact mut |
| Therapy | StAx-35 |
| Indication/Tumor Type | colon cancer |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| APC inact mut | colon cancer | sensitive | StAx-35 | Preclinical | Actionable | In a preclinical study, StAx-35 inhibited proliferation of colon cancer cell lines carrying APC deletions in culture (PMID: 23071338). | 23071338 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (23071338) | Inhibition of oncogenic Wnt signaling through direct targeting of β-catenin. | Full reference... |