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Molecular Profile | BRAF V600E |
Therapy | PD-0325901 |
Indication/Tumor Type | colon cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF V600E | colon cancer | sensitive | PD-0325901 | Preclinical - Cell line xenograft | Actionable | In a preclinical study, PD-0325901 demonstrated antitumor activity against BRAF V600E colon cancer cell line xenografts (PMID: 16273091). | 16273091 |
PubMed Id | Reference Title | Details |
---|---|---|
(16273091) | BRAF mutation predicts sensitivity to MEK inhibition. | Full reference... |