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| Molecular Profile | BTK C481S |
| Therapy | Zanubrutinib |
| Indication/Tumor Type | chronic lymphocytic leukemia/small lymphocytic lymphoma |
| Response Type | resistant |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| BTK C481S | chronic lymphocytic leukemia/small lymphocytic lymphoma | resistant | Zanubrutinib | Guideline | Actionable | Brukinsa (zanubrutinib) is not indicated for use in patients with Imbruvica (ibrutinib)-refractory chronic lymphocytic leukemia/small lymphocytic lymphoma harboring BTK C481S (NCCN.org). | detail... |
| PubMed Id | Reference Title | Details |
|---|---|---|
| NCCN.org | Full reference... |