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Molecular Profile | BRAF mutant |
Therapy | Obatoclax |
Indication/Tumor Type | Advanced Solid Tumor |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF mutant | Advanced Solid Tumor | sensitive | Obatoclax | Preclinical | Actionable | In a preclinical study, obatoclax decreased proliferation in human tumor cell lines with BRAF mutation in culture (PMID: 22460902). | 22460902 |
PubMed Id | Reference Title | Details |
---|---|---|
(22460902) | Systematic identification of genomic markers of drug sensitivity in cancer cells. | Full reference... |