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| Molecular Profile | FGFR2 positive |
| Therapy | Alofanib |
| Indication/Tumor Type | ovarian cancer |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| FGFR2 positive | ovarian cancer | predicted - sensitive | Alofanib | Preclinical - Cell culture | Actionable | In a preclinical study, Alofanib (RPT835) inhibited growth in an ovarian cancer cell line expressing FGFR2 in culture (PMID: 27136102). | 27136102 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (27136102) | Targeting FGFR2 with alofanib (RPT835) shows potent activity in tumour models. | Full reference... |