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Molecular Profile | CD274 positive |
Therapy | CS1003 |
Indication/Tumor Type | colon cancer |
Response Type | sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
CD274 positive | colon cancer | sensitive | CS1003 | Preclinical | Actionable | In a preclinical study, CS1003 inhibited tumor growth in a xenograft model of CD274 (PD-L1)-positive colon cancer (PMID: 32467569). | 32467569 |
PubMed Id | Reference Title | Details |
---|---|---|
(32467569) | CS1003, a novel human and mouse cross-reactive PD-1 monoclonal antibody for cancer therapy. | Full reference... |