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Molecular Profile | BRAF V600E |
Therapy | Vemurafenib |
Indication/Tumor Type | IDH-wildtype glioblastoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF V600E | IDH-wildtype glioblastoma | predicted - sensitive | Vemurafenib | Case Reports/Case Series | Actionable | In a clinical case study, Zelboraf (vemurafenib) treatment resulted in disease stability over 15 months in a patient with epithelioid glioblastoma harboring BRAF V600E, who previously progressed on conventional treatment options (PMID: 34232949). | 34232949 |
PubMed Id | Reference Title | Details |
---|---|---|
(34232949) | Effective treatment of a BRAF V600E-mutant epithelioid glioblastoma patient by vemurafenib: a case report. | Full reference... |