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Molecular Profile | BRAF D594G |
Therapy | Ulixertinib |
Indication/Tumor Type | melanoma |
Response Type | predicted - sensitive |
Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
---|---|---|---|---|---|---|---|
BRAF D594G | melanoma | predicted - sensitive | Ulixertinib | Case Reports/Case Series | Actionable | In a clinical case study, Ulixertinib (BVD-523) treatment resulted in a histologic response allowing for surgical resection in a patient with metastatic melanoma harboring BRAF D594G (PMID: 35551160; NCT04566393). | 35551160 |
PubMed Id | Reference Title | Details |
---|---|---|
(35551160) | Case report: response to the ERK1/2 inhibitor ulixertinib in BRAF D594G cutaneous melanoma. | Full reference... |