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| Molecular Profile | CSF1R positive |
| Therapy | Sorafenib |
| Indication/Tumor Type | Hodgkin's lymphoma |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| CSF1R positive | Hodgkin's lymphoma | sensitive | Sorafenib | Preclinical | Actionable | In a preclinical study, Nexavar (sorafenib) inhibited CSF1R phosphorylation and induced apoptosis in Hodgkin's lymphoma cells in culture (PMID: 21517818) | 21517818 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (21517818) | BAY 43-9006/Sorafenib blocks CSF1R activity and induces apoptosis in various classical Hodgkin lymphoma cell lines. | Full reference... |