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| Molecular Profile | ATR positive |
| Therapy | VE-821 |
| Indication/Tumor Type | breast cancer |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| ATR positive | breast cancer | predicted - sensitive | VE-821 | Preclinical - Cell culture | Actionable | In a preclinical study, human breast cancer cell lines demonstrated sensitivity to VE-821 in culture, resulting in decreased cell survival (PMID: 25468710). | 25468710 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (25468710) | Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer. | Full reference... |