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| Molecular Profile | KIT V560D |
| Therapy | Sorafenib |
| Indication/Tumor Type | Advanced Solid Tumor |
| Response Type | sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| KIT V560D | Advanced Solid Tumor | sensitive | Sorafenib | Preclinical | Actionable | In a preclinical study, transformed cells expressing KIT V560D were sensitive to Nexavar (sorafenib) in culture (PMID: 22665524). | 22665524 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (22665524) | Sorafenib inhibits many kinase mutations associated with drug-resistant gastrointestinal stromal tumors. | Full reference... |