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| Molecular Profile | BRAF V600E |
| Therapy | Vemurafenib |
| Indication/Tumor Type | ovary serous adenocarcinoma |
| Response Type | predicted - sensitive |
| Molecular Profile | Indication/Tumor Type | Response Type | Therapy Name | Approval Status | Evidence Type | Efficacy Evidence | References |
|---|---|---|---|---|---|---|---|
| BRAF V600E | ovary serous adenocarcinoma | predicted - sensitive | Vemurafenib | Case Reports/Case Series | Actionable | In a clinical case study, Zelboraf (vemurafenib) treatment resulted in a partial response lasting more than 21 months in a patient with low grade serous ovarian adenocarcinoma harboring BRAF V600E (PMID: 26490654). | 26490654 |
| PubMed Id | Reference Title | Details |
|---|---|---|
| (26490654) | Sustained response to vemurafenib in a low grade serous ovarian cancer with a BRAF V600E mutation. | Full reference... |